CellParameterisation.cc

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//
// This example is provided by the Geant4-DNA collaboration
// Any report or published results obtained using the Geant4-DNA software 
// shall cite the following Geant4-DNA collaboration publication:
// Med. Phys. 37 (2010) 4692-4708
// The Geant4-DNA web site is available at http://geant4-dna.org
// 
// If you use this example, please cite the following publication:
// Rad. Prot. Dos. 133 (2009) 2-11

#include "CellParameterisation.hh"
#include "G4LogicalVolume.hh"
#include "G4SystemOfUnits.hh"

//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......

// SINGLETON
CellParameterisation * CellParameterisation::gInstance = 0;


CellParameterisation::CellParameterisation
(G4Material * nucleus1,  G4Material * cytoplasm1,
 G4Material * nucleus2,  G4Material * cytoplasm2,
 G4Material * nucleus3,  G4Material * cytoplasm3
 )
{
   fNucleusMaterial1   = nucleus1;
   fCytoplasmMaterial1 = cytoplasm1;
   fNucleusMaterial2   = nucleus2;
   fCytoplasmMaterial2 = cytoplasm2;
   fNucleusMaterial3   = nucleus3;
   fCytoplasmMaterial3 = cytoplasm3;

   G4int ncols,nlines;
   G4int shiftX, shiftY, shiftZ;
   G4double x,y,z,mat,den,tmp,density;  
   G4double denCyto1, denCyto2, denCyto3, denNucl1, denNucl2, denNucl3;
   
   density=0;
   denCyto1=0;
   denCyto2=0;
   denCyto3=0;
   denNucl1=0;
   denNucl2=0;
   denNucl3=0;
   
   ncols=0; nlines=0;
    
   // READ PHANTOM 
   
   fNucleusMass = 0;
   fCytoplasmMass = 0;
    
   FILE *fMap;
   fMap = fopen("phantom.dat","r");
    
   while (1) 
   {  
      if (nlines == 0) 
      {
        ncols = fscanf(fMap,"%i %i %i",&fPhantomTotalPixels,&fNucleusTotalPixels,&fCytoplasmTotalPixels);
  fMapCell    = new G4ThreeVector[fPhantomTotalPixels];
        fMaterial   = new G4double[fPhantomTotalPixels];
        fMass       = new G4double[fPhantomTotalPixels];
        fTissueType = new G4int[fPhantomTotalPixels];
      }
      
      if (nlines == 1)
      { 
        ncols = fscanf(fMap,"%lf %lf %lf",&fDimCellBoxX,&fDimCellBoxY,&fDimCellBoxZ);
        
  fDimCellBoxX=fDimCellBoxX*micrometer;
        fDimCellBoxY=fDimCellBoxY*micrometer;
        fDimCellBoxZ=fDimCellBoxZ*micrometer;
      }

      if (nlines == 2) ncols = fscanf(fMap,"%i %i %i",&shiftX,&shiftY,&shiftZ); // VOXEL SHIFT IN Z ASSUMED TO BE NEGATIVE
      
      if (nlines == 3) ncols = fscanf(fMap,"%lf %lf %lf",&denCyto1, &denCyto2, &denCyto3);
      
      if (nlines == 4) ncols = fscanf(fMap,"%lf %lf %lf",&denNucl1, &denNucl2, &denNucl3);
      
      if (nlines >  4) ncols = fscanf(fMap,"%lf %lf %lf %lf %lf %lf",&x,&y,&z,&mat,&den,&tmp);
      
      if (ncols  <  0) break;

      G4ThreeVector v(x+shiftX,y+shiftY,z-1500/(fDimCellBoxZ/micrometer)-shiftZ); // VOXEL SHIFT IN ORDER TO CENTER PHANTOM
      
      if (nlines>4) 
      {

    fMapCell[nlines-5]=v; 
    fMaterial[nlines-5]=mat;
    fMass[nlines-5]=den;
    
    // fTissueType: 1 is Cytoplasm - 2 is Nucleus
    
          if( fMaterial[nlines-5] == 2 ) // fMaterial 2 is nucleus
          {
      if( fMass[nlines-5] == 1 ) 
    {
      fTissueType[nlines-5]=2;
    }
      if( fMass[nlines-5] == 2 ) 
    {
      fTissueType[nlines-5]=2;
    }
      if( fMass[nlines-5] == 3 ) 
    {
      fTissueType[nlines-5]=2;
    }
    } 
  
          else if( fMaterial[nlines-5] == 1 ) // fMaterial 1 is cytoplasm
    {
      if( fMass[nlines-5] == 1 ) 
    {
      fTissueType[nlines-5]=1;
    }
      if( fMass[nlines-5] == 2 ) 
    {
      fTissueType[nlines-5]=2;
    }
      if( fMass[nlines-5] == 3 ) 
    {
      fTissueType[nlines-5]=1;
    }
    } 
            
    //    
        
    if (std::abs(mat-2)<1.e-30) // NUCLEUS
        {
      if (std::abs(den-1)<1.e-30) density = denNucl1*(g/cm3);
      if (std::abs(den-2)<1.e-30) density = denNucl2*(g/cm3);
      if (std::abs(den-3)<1.e-30) density = denNucl3*(g/cm3);
      fNucleusMass   = fNucleusMass   + density * fDimCellBoxX * fDimCellBoxY * fDimCellBoxZ ;
        }

          if (std::abs(mat-1)<1.e-30) // CYTOPLASM
        { 
      if (std::abs(den-1)<1e-30) density = denCyto1*(g/cm3);
      if (std::abs(den-2)<1e-30) density = denCyto2*(g/cm3);
      if (std::abs(den-3)<1e-30) density = denCyto3*(g/cm3);
      fCytoplasmMass = fCytoplasmMass + density * fDimCellBoxX * fDimCellBoxY * fDimCellBoxZ ;
    }
    
      }   

      nlines++;    
   }
   fclose(fMap);

  // NUCLEUS IN GREEN 
  
  fNucleusAttributes1 = new G4VisAttributes;
  fNucleusAttributes1->SetColour(G4Colour(0,.8,0));
  fNucleusAttributes1->SetForceSolid(false);

  fNucleusAttributes2 = new G4VisAttributes;
  fNucleusAttributes2->SetColour(G4Colour(0,.9,0));
  fNucleusAttributes2->SetForceSolid(false);

  fNucleusAttributes3 = new G4VisAttributes;
  fNucleusAttributes3->SetColour(G4Colour(0,1,0));
  fNucleusAttributes3->SetForceSolid(false);

  // CYTOPLASM IN RED
  
  fCytoplasmAttributes1 = new G4VisAttributes;
  fCytoplasmAttributes1->SetColour(G4Colour(1,0,0));
  fCytoplasmAttributes1->SetForceSolid(false);

  fCytoplasmAttributes2 = new G4VisAttributes; // nucleoli in yellow
  fCytoplasmAttributes2->SetColour(G4Colour(1.,1.,0));
  fCytoplasmAttributes2->SetForceSolid(false);

  fCytoplasmAttributes3 = new G4VisAttributes;
  fCytoplasmAttributes3->SetColour(G4Colour(1,0,0));
  fCytoplasmAttributes3->SetForceSolid(false);

  //

  gInstance = this;
 
 }

//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......

CellParameterisation::~CellParameterisation()
{
  delete[] fMapCell;
  delete[] fMaterial;
  delete[] fMass;
  delete[] fTissueType;
}

//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......

void CellParameterisation::ComputeTransformation
(const G4int copyNo, G4VPhysicalVolume* physVol) const
{
  G4ThreeVector origin
  (
      fMapCell[copyNo].x()*fDimCellBoxX,
      fMapCell[copyNo].y()*fDimCellBoxY,
      fMapCell[copyNo].z()*fDimCellBoxZ
  );

  physVol->SetTranslation(origin);   
}

//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......

void CellParameterisation::ComputeDimensions
(G4Box&, const G4int, const G4VPhysicalVolume*) const
{}

//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......

G4Material*
CellParameterisation::ComputeMaterial(const G4int copyNo,
                                      G4VPhysicalVolume* physVol,
                                      const G4VTouchable*)
{
    if( fMaterial[copyNo] == 2 ) // fMaterial 2 is nucleus
        {
   if( fMass[copyNo] == 1 ) 
    {
      physVol->GetLogicalVolume()->SetVisAttributes( fNucleusAttributes1 );
      return fNucleusMaterial1;
    }
   if( fMass[copyNo] == 2 ) 
    {
      physVol->GetLogicalVolume()->SetVisAttributes( fNucleusAttributes2 );
      return fNucleusMaterial2;
    }
   if( fMass[copyNo] == 3 ) 
    {
      physVol->GetLogicalVolume()->SetVisAttributes( fNucleusAttributes3 );
      return fNucleusMaterial3;
    }
  } 
  
    else if( fMaterial[copyNo] == 1 ) // fMaterial 1 is cytoplasm
  {
   if( fMass[copyNo] == 1 ) 
    {
      physVol->GetLogicalVolume()->SetVisAttributes( fCytoplasmAttributes1 );
      return fCytoplasmMaterial1;
    }
   if( fMass[copyNo] == 2 ) 
    {
      // nucleoli so taken as nucleus !
      physVol->GetLogicalVolume()->SetVisAttributes( fCytoplasmAttributes2 );
      return fCytoplasmMaterial2;
    }
   if( fMass[copyNo] == 3 ) 
    {
      physVol->GetLogicalVolume()->SetVisAttributes( fCytoplasmAttributes3 );
      return fCytoplasmMaterial3;
    }
  } 

    return physVol->GetLogicalVolume()->GetMaterial();
}